CME

Continuing Medical Education

Familial Multiple Lipomatosis: Report of a New Family

Gologorsky Y, Gologorsky D, Yarygina AS, Surti U, Zirwas MJ

Cutis. 2007;79:227-232.

Familial multiple lipomatosis (FML) is a rare entity. We report a family with this disease. Karyotypic analysis was performed on tissue isolated from excised lipomas and peripheral blood. No chromosomal abnormalities were found. This is the first report of karyotypic analysis of lipomas removed from a patient with FML. The finding of a normal karyotype is important because approximately 25% of spontaneous lipomas will have abnormal karyotypes; therefore, we felt there was a significant probability that familial lipomas in FML would have abnormal karyotypes.

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