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Department

Therapeutics for the Clinician
Managing Simple Chronic Paronychia and Onycholysis With Ciclopirox 0.77% and an Irritant-Avoidance Regimen
Daniel CR III, Daniel MP, Daniel J, Sullivan S, Bell FE
Cutis. 2004;73:81-85.

Dermatologists and other physicians frequently encounter simple chronic paronychia and onycholysis. In addition to strict avoidance of contact irritants, a broad-spectrum topical antifungal agent has been recommended. We conducted an examination of treatment with this type of agent and an assessment of the efficacy of ciclopirox 0.77% topical suspension in combination with a strict irritant-avoidance regiment. Early results of a pilot study (N=44) using ciclopirox 0.77% topical suspension in patients diagnosed with simple chronic paronychia and/or onycholysis show excellent therapeutic outcomes of a combined regimen of a broad-spectrum topical antifungal agent such as ciclopirox and contact-irritant avoidance in this patient population.


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