Onycholysis may be defined as separation of the nail plate from the underlying nail bed due to disruption of the onychocorneal band. Simple onycholysis is a common condition seen in the dermatologist’s office. It is not associated with inheritance, systemic diseases or drugs, dermatophyte infections, warts or neoplasms, or primary dermatologic disease such as psoriasis or lichen planus. It is generally assumed that the longer the disorder has been present, the less likely it is to resolve. As a result, we provide directions that should be given to patients presenting with simple onycholysis.