CME

Continuing Medical Education

Tuberculosis Verrucosa Cutis Presenting as an Annular Hyperkeratotic Plaque

Janjua SA, Khachemoune A, Guillen S

Cutis. 2006;78:309-316.

Tuberculosis verrucosa cutis (TVC) is a form of cutaneous tuberculosis that results from accidental inoculation of Mycobacterium tuberculosis in a previously infected or sensitized individual with a moderate to high degree of slowly evolving cell-mediated immunity. TVC usually begins as a solitary papulonodule following a trivial injury or trauma on one of the extremities that soon acquires a scaly and verrucous surface. The lesion, which is usually persistent, expands slowly over several months or years with or without central clearing and atrophy. We report a case of TVC in a 15-year-old girl that was undiagnosed for 10 years. The diagnosis was confirmed by a positive mycobacterial culture and characteristic histopathologic findings of the biopsy specimens. The patient responded well to antituberculous therapy (ATT), and the lesion resolved with residual scarring.

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