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Original Article
Imiquimod Cream 5% for the Treatment of Arsenic-Induced Cutaneous Neoplasms
Lonergan CL, McNamara EK, Cordoro KM, Greer KE
Cutis
. 2010;85:199-202.
Long-term exposure to arsenic has been linked to the development of numerous cutaneous neoplasms including arsenical keratoses, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs). We report a patient with a remote history of psoriasis treated with arsenic who subsequently developed more than 40 nonmelanoma skin cancers as well as arsenical keratoses. This patient had a remarkable response to imiquimod cream 5% applied once daily to affected areas for 6 weeks with complete resolution of all cutaneous neoplasms and no evidence of recurrence in more than 3 years of clinical surveillance.
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