Department

Highlighting Skin of Color

An Open Label Study of Clobetasol Propionate 0.05% and Betamethasone Valerate 0.12% Foams in the Treatment of Mild to Moderate Acne Keloidalis

Callender VD, Young CM, Haverstock CL, Carroll CL, Feldman SR

Cutis. 2005;75:317-321.

Acne keloidalis (AK) is a disease affecting primarily African American men. Topical steroids are a widely accepted treatment of AK; however, no studies have been published investigating their effectiveness. The purpose of this open-label study was to assess the efficacy and tolerability of clobetasol propionate 0.05% and betamethasone valerate 0.12% foams in the treatment of AK in 20 African American patients. These patients were treated for 8 to 12 weeks using a pulsed-dose regimen. We found topical clobetasol propionate foam to be effective in improving AK, and our patients found the foam vehicle to be cosmetically acceptable.

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