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CME
Continuing Medical Education
Keratoacanthoma Centrifugum Marginatum: A Diagnostic and Therapeutic Challenge
Divers AK, Correale D, Lee JB
Cutis
. 2004;73:257-262.
A keratoacanthoma centrifugum marginatum (KACM) may pose a diagnostic and therapeutic challenge. Clinically and histologically, it may resemble mycobacterial or deep fungal infection or halogenoderma. Therapy can be challenging because the lesion can expand to a great size. We report on a patient with multiple lesions of KACM. The diagnostic difficulty and the therapeutic failure of imiquimod, intralesional methotrexate (MTX), and isotretinoin, as well as the therapeutic success of 5-fluorouracil (5-FU) cream, are discussed.
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