Original Article

Pemphigus Erythematosus Associated With Anti-DNA Antibodies and Multiple Anti-ENA Antibodies: A Case Report

Scheinfeld NS, Howe KL, DiCostanzo DP, Craig E, Cohen SR

Cutis. 2003;71:303-306.

Pemphigus erythematosus (PE) is an autoimmune blistering disease combining features of pemphigus foliaceus (PF) and systemic lupus erythematosus (SLE). We report a case of PE associated with anti–double-stranded DNA (anti-dsDNA), anti-Smith (anti-Sm), anti-Ro (anti-SSA), and antiribonucleoprotein (anti-RNP) antibodies. This case required extensive immunosuppressive therapy. We treated our patient with a combination of systemic steroids, intramuscular gold injections, azathioprine, and hydroxychloroquine. The patient’s response was complete remission—evaluated clinically, serologically, and immunohistochemically.

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