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Original Article

Severe Psoriasis With Positive Tuberculosis Test and Treatment With Biologic Therapy: A Case Report
Skroza N, Proietti I, Bernardini N, La Viola G, Nicolucci F, Tolino E, Zuber S, Potenza C
Cutis. 2012;90:120-122.

Psoriasis and tuberculosis (TB) are 2 conditions with high prevalence in the general population, often present simultaneously in the same patient. The crucial cytokine involved in the pathogenesis of psoriasis, tumor necrosis factor α (TNF-α), also is important in defending against mycobacteria. Therefore, it is important to screen patients for a latent TB infection (LTBI) while they are undergoing treatment with TNF-α antagonists. We present a case of a patient with psoriasis and LTBI who underwent treatment with etanercept.


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